Week 6: Quality Improvement Using Evidence-Based Practice in Nursing 8282 unread replies.100100 replies. This week’s graded discussion topic relates to the following Course Outcome (CO). CO3 Examine culture of safety principles that improve patient outcomes based on current evidence. (POs 7 and 8) Consider a single nursing care issue at your facility where quality has already been improved by implementation of evidence. Answer the following: How was evidence on that topic located in scholarly professional nursing journal articles and evaluated? What was the implementation plan? How was the improvement in quality measured after the implementation? What do you suggest that would have improved this implementation and maintenance of improved quality?